Basic Information
| LncRNA/CircRNA Name | RP11-624C23.1 |
| Synonyms | NA |
| Region | GRCh38_8:24295814-24912073 |
| Ensemble | NA |
| Refseq | NA |
Classification Information
| Regulatory Mechanism | Biological Function | Clinical Application | |||
|---|---|---|---|---|---|
| TF | Immune | Survival | |||
| Enhancer | Apoptosis | Drug | |||
| Variant | Cell Growth | Circulating | |||
| MiRNA | EMT | Metastasis | |||
| Methylation | Coding Ability | Recurrence |
Cancer&Entry Information
| Cancer Name | childhood acute lymphoblastic leukemia |
| ICD-0-3 | NA |
| Methods | RNA-seq, qPCR |
| Sample | cell lines (The Reh pre-B cALL, GM12878 B-lymphoblast ) |
| Expression Pattern | down-regulated |
| Function Description | These results indicate that silencing RP11-624C23.1 or RP11-203E8 could provide a selective advantage to leukemic cells by increasing resistance to genotoxic stress, possibly by modulating the DDR pathway. |
| Pubmed ID | 29113332 |
| Year | 2017 |
| Title | LncRNAs downregulated in childhood acute lymphoblastic leukemia modulate apoptosis, cell migration, and DNA damage response. |
External Links
| Links for RP11-624C23.1 | GenBank HGNC NONCODE |
| Links for childhood acute lymphoblastic leukemia | OMIM COSMIC |