Basic Information
| LncRNA/CircRNA Name | RP11-874J12.4 |
| Synonyms | NA |
| Region | GRCh38_18:3653410-3656282 |
| Ensemble | NA |
| Refseq | NA |
Classification Information
| Regulatory Mechanism | Biological Function | Clinical Application | |||
|---|---|---|---|---|---|
| TF | Immune | Survival | |||
| Enhancer | Apoptosis | apoptosis | Drug | ||
| Variant | Cell Growth | Circulating | |||
| MiRNA | EMT | Metastasis | |||
| Methylation | Coding Ability | Recurrence |
Cancer&Entry Information
| Cancer Name | oral squamous cell carcinoma |
| ICD-0-3 | C06.9 |
| Methods | qRT-PCR, Western blot |
| Sample | OSCC tissues,cell lines |
| Expression Pattern | up-regulated |
| Function Description | RP11-874J12.4 directly binds to and regulates miR-19a-5p.RP11-874J12.4 and miR-19a-5p form a negative regulatory loop that inhibits the expression of miR-19a-5p in OSCC. |
| Pubmed ID | 32004389 |
| Year | 2020 |
| Title | RP11-874J12.4 promotes oral squamous cell carcinoma tumorigenesis via the miR-19a-5p/EBF1 axis |
External Links
| Links for RP11-874J12.4 | GenBank HGNC NONCODE |
| Links for oral squamous cell carcinoma | OMIM COSMIC |