Basic Information
| LncRNA/CircRNA Name | BlackMamba |
| Synonyms | NA |
| Region | NA |
| Ensemble | NA |
| Refseq | NA |
Classification Information
| Regulatory Mechanism | Biological Function | Clinical Application | |||
|---|---|---|---|---|---|
| TF | Immune | Survival | |||
| Enhancer | Apoptosis | apoptosis | Drug | ||
| Variant | Cell Growth | Circulating | |||
| MiRNA | EMT | Metastasis | |||
| Methylation | Coding Ability | Recurrence |
Cancer&Entry Information
| Cancer Name | anaplastic large cell lymphoma |
| ICD-0-3 | NA |
| Methods | qRT-PCR, Western blot |
| Sample | ALCL tissues,cell lines |
| Expression Pattern | differential expression |
| Function Description | BlackMamba interacts with the DNA helicase HELLS controlling its recruitment to the promoter regions of cell-architecture-related genes, fostering their expression. |
| Pubmed ID | 32123306 |
| Year | 2020 |
| Title | The novel lncRNA BlackMamba controls the neoplastic phenotype of ALK ??anaplastic large cell lymphoma by regulating the DNA helicase HELLS |
External Links
| Links for BlackMamba | GenBank HGNC NONCODE |
| Links for anaplastic large cell lymphoma | OMIM COSMIC |