Basic Information
| LncRNA/CircRNA Name | SAMMSON |
| Synonyms | NA |
| Region | GRCh38_3:69999550-70518064 |
| Ensemble | ENSG00000240405 |
| Refseq | NR_110000 |
Classification Information
| Regulatory Mechanism | Biological Function | Clinical Application | |||
|---|---|---|---|---|---|
| TF | Immune | Survival | |||
| Enhancer | Apoptosis | Drug | |||
| Variant | Cell Growth | Circulating | |||
| MiRNA | EMT | Metastasis | |||
| Methylation | Coding Ability | Recurrence |
Cancer&Entry Information
| Cancer Name | hepatocellular carcinoma |
| ICD-0-3 | C22.0 |
| Methods | qRT-PCR etc. |
| Sample | adjacent non-cancer and HCC tissues ,human HCC cell lines(SNU-182 and SNU-398) |
| Expression Pattern | up-regulated |
| Function Description | SAMMSON was up-regulated in HCC tissues, and patients with high levels of SAMMSON in HCC tissues had significantly lower overall rate within 5 years after admission.miR-9-3p was down-regulated in HCC tissues and inversely correlated with SAMMSON.SAMMSON expression was not significantly affected by HBV and HCV infections in HCC patients.SAMMSON negatively regulated miR-9-3p in HCC cells to promote cancer cell migration and invasion. |
| Pubmed ID | 31164410 |
| Year | 2019 |
| Title | LncRNA SAMMSON Negatively Regulates miR-9-3p in Hepatocellular Carcinoma Cells and Has Prognostic Values |
External Links
| Links for SAMMSON | GenBank HGNC NONCODE |
| Links for hepatocellular carcinoma | OMIM COSMIC |