Basic Information
| LncRNA/CircRNA Name | BM742401 |
| Synonyms | GATA6-AS1, BM742401, locus5689 |
| Region | GRCh38_18:22166898-22168968 |
| Ensemble | ENSG00000266010 |
| Refseq | NR_102763 |
Classification Information
| Regulatory Mechanism | Biological Function | Clinical Application | |||
|---|---|---|---|---|---|
| TF | Immune | Survival | |||
| Enhancer | Apoptosis | apoptosis | Drug | ||
| Variant | Cell Growth | Circulating | |||
| MiRNA | EMT | Metastasis | |||
| Methylation | Coding Ability | Recurrence |
Cancer&Entry Information
| Cancer Name | gastric cancer |
| ICD-0-3 | C16 |
| Methods | RNA-seq, qPCR, in vitro knockdown etc. |
| Sample | gastric cancer tissues, cell line (B16F1) |
| Expression Pattern | down-regulated |
| Function Description | BM742401 was downregulated in cancer, and its downregulation was associated with poor survival in gastric cancer patients. Ectopic overexpression of BM742401 inhibited metastasis-related phenotypes and decreased the concentration of extracellular MMP9. |
| Pubmed ID | 23846333 |
| Year | 2013 |
| Title | A known expressed sequence tag, BM742401, is a potent lincRNA inhibiting cancer metastasis. |
External Links
| Links for BM742401 | GenBank HGNC NONCODE |
| Links for gastric cancer | OMIM COSMIC |