Basic Information
| LncRNA/CircRNA Name | SBF2-AS1 |
| Synonyms | NA |
| Region | GRCh38_11:9758292-9811319 |
| Ensemble | ENSG00000246273 |
| Refseq | NR_036485 |
Classification Information
| Regulatory Mechanism | Biological Function | Clinical Application | |||
|---|---|---|---|---|---|
| TF | Immune | Survival | |||
| Enhancer | Apoptosis | Drug | |||
| Variant | Cell Growth | Circulating | |||
| MiRNA | EMT | Metastasis | |||
| Methylation | Coding Ability | Recurrence |
Cancer&Entry Information
| Cancer Name | non small cell lung cancer |
| ICD-0-3 | C34 |
| Methods | qPCR, Western blot, luciferase reporter assay, knockdown etc. |
| Sample | NSCLC tissues and adjacent tissues, cell lines (A549, H1299, H460, H226, L78 cells,HPAEpiC) |
| Expression Pattern | up-regulated |
| Function Description | SBF2-AS1 was upregulated in both NSCLC tissues and cell lines. Patients with high levels of SBF2-AS1 have larger tumors, higher malignancy, and poor prognosis. |
| Pubmed ID | 32364763 |
| Year | 2020 |
| Title | E2F1-Induced Overexpression of Long Noncoding RNA SBF2-AF1 Promotes Non-Small-Cell Lung Cancer Metastasis through Regulating miR-362-3p/GRB2 Axis. |
External Links
| Links for SBF2-AS1 | GenBank HGNC NONCODE |
| Links for non small cell lung cancer | OMIM COSMIC |