Basic Information
| LncRNA/CircRNA Name | SLINKY |
| Synonyms | NA |
| Region | NA |
| Ensemble | NA |
| Refseq | NA |
Classification Information
| Regulatory Mechanism | Biological Function | Clinical Application | |||
|---|---|---|---|---|---|
| TF | Immune | Survival | |||
| Enhancer | Apoptosis | Drug | |||
| Variant | Cell Growth | Circulating | |||
| MiRNA | EMT | Metastasis | |||
| Methylation | Coding Ability | Recurrence |
Cancer&Entry Information
| Cancer Name | kidney cancer |
| ICD-0-3 | C64 |
| Methods | qPCR, RIP |
| Sample | Clear cell renal cell carcinoma cell lines |
| Expression Pattern | up-regulated |
| Function Description | In ccRCC cell lines, SLINKY knockdown reduced cancer cell proliferation (with cell-cycle G1 arrest) and induced transcriptome changes enriched for cell proliferation and survival processes. Notably, the genes affected by SLINKY knockdown in cell lines were themselves prognostic and correlated with SLINKY expression in the ccRCC patient samples. |
| Pubmed ID | 28423633 |
| Year | 2017 |
| Title | Novel lincRNA SLINKY is a prognostic biomarker in kidney cancer |
External Links
| Links for SLINKY | GenBank HGNC NONCODE |
| Links for kidney cancer | OMIM COSMIC |