Basic Information
| LncRNA/CircRNA Name | SNHG1 |
| Synonyms | SNHG1, LINC00057, NCRNA00057, U22HG, UHG, lncRNA16 |
| Region | GRCh38_11:62851988-62855914 |
| Ensemble | ENSG00000255717 |
| Refseq | NR_003098 |
Classification Information
| Regulatory Mechanism | Biological Function | Clinical Application | |||
|---|---|---|---|---|---|
| TF | Immune | Survival | |||
| Enhancer | Apoptosis | Drug | |||
| Variant | Cell Growth | Circulating | |||
| MiRNA | EMT | Metastasis | |||
| Methylation | Coding Ability | Recurrence |
Cancer&Entry Information
| Cancer Name | breast cancer |
| ICD-0-3 | C50 |
| Methods | qPCR, Western blot, Luciferase reporter assay etc. |
| Sample | human breast cancer tumor tissues and matched normal breast tissues,cell lines(MCF7, and T47D,,ER??PR??Her2?? MDA-MB-231 and MDA-MB-468) |
| Expression Pattern | up-regulated |
| Function Description | SNHG1 is overexpressed in breast cancer tumor tissues and cell lines, notably in ER??PR??breast cancer.SNHG1 is located in nuclear and cytoplasmic regions and sponges miR-573 in breast cancer cells. |
| Pubmed ID | 32323846 |
| Year | 2020 |
| Title | Long non-coding RNA SNHG1 promotes breast cancer progression by regulation of LMO4 |
External Links
| Links for SNHG1 | GenBank HGNC NONCODE |
| Links for breast cancer | OMIM COSMIC |