Basic Information
| LncRNA/CircRNA Name | SNHG1 |
| Synonyms | SNHG1, LINC00057, NCRNA00057, U22HG, UHG, lncRNA16 |
| Region | GRCh38_11:62851988-62855914 |
| Ensemble | ENSG00000255717 |
| Refseq | NR_003098 |
Classification Information
| Regulatory Mechanism | Biological Function | Clinical Application | |||
|---|---|---|---|---|---|
| TF | Immune | Survival | |||
| Enhancer | Apoptosis | Drug | |||
| Variant | Cell Growth | Circulating | |||
| MiRNA | EMT | Metastasis | |||
| Methylation | Coding Ability | Recurrence |
Cancer&Entry Information
| Cancer Name | non small cell lung cancer |
| ICD-0-3 | C34 |
| Methods | qPCR, Western blot, Luciferase reporter assay etc |
| Sample | NSCLC tissues,cell line (BEAS-2B,H23) |
| Expression Pattern | up-regulated |
| Function Description | Expression of SNHG1 and FRAT1 were increased in NSCLC tissues and cells.SNHG1 silencing repressed proliferation, induced apoptosis and suppressed migration and invasion of NSCLC cells. |
| Pubmed ID | 31788970 |
| Year | 2019 |
| Title | LncRNA SNHG1 Influences Cell Proliferation, Migration, Invasion, and Apoptosis of Non-Small Cell Lung Cancer Cells via the miR-361-3p/FRAT1 Axis |
External Links
| Links for SNHG1 | GenBank HGNC NONCODE |
| Links for non small cell lung cancer | OMIM COSMIC |