Basic Information
| LncRNA/CircRNA Name | SNHG1 |
| Synonyms | SNHG1, LINC00057, NCRNA00057, U22HG, UHG, lncRNA16 |
| Region | GRCh38_11:62851988-62855914 |
| Ensemble | ENSG00000255717 |
| Refseq | NR_003098 |
Classification Information
| Regulatory Mechanism | Biological Function | Clinical Application | |||
|---|---|---|---|---|---|
| TF | Immune | Survival | |||
| Enhancer | Apoptosis | Drug | |||
| Variant | Cell Growth | Circulating | |||
| MiRNA | EMT | Metastasis | |||
| Methylation | Coding Ability | Recurrence |
Cancer&Entry Information
| Cancer Name | neuroblastoma |
| ICD-0-3 | NA |
| Methods | qPCR |
| Sample | cell lines (SK-N-DZ, SK-N-SH, SK-N-BE(2)-C) |
| Expression Pattern | up-regulated |
| Function Description | In conclusion, our study unveils that SNHG1 is up-regulated by MYCN amplification and could be a potential prognostic biomarker for high-risk NB intervention. Kaplan-Meier analysis shows that higher expression of SNHG1 is significantly associated with poor patient survival. |
| Pubmed ID | 27517149 |
| Year | 2016 |
| Title | Co-expression analysis identifies long noncoding RNA SNHG1 as a novel predictor for event-free survival in neuroblastoma |
External Links
| Links for SNHG1 | GenBank HGNC NONCODE |
| Links for neuroblastoma | OMIM COSMIC |