Basic Information
| LncRNA/CircRNA Name | SNHG11 |
| Synonyms | NA |
| Region | GRCh38_20:38446578-38450921 |
| Ensemble | ENSG00000174365 |
| Refseq | NR_003239 |
Classification Information
| Regulatory Mechanism | Biological Function | Clinical Application | |||
|---|---|---|---|---|---|
| TF | Immune | Survival | |||
| Enhancer | Apoptosis | Drug | |||
| Variant | Cell Growth | Circulating | |||
| MiRNA | EMT | Metastasis | |||
| Methylation | Coding Ability | Recurrence |
Cancer&Entry Information
| Cancer Name | lung cancer |
| ICD-0-3 | C34 |
| Methods | qPCR, Western blot, Luciferase reporter assay, RIP etc. |
| Sample | lung cancer tissues, cell lines(A549, H1299, H460, and SPCA1) w |
| Expression Pattern | up-regulated |
| Function Description | qRT-PCR also demonstrated that the expression of SNHG11 was higher in lung cancer cells.SNHG11 activates Wnt/?-catenin pathway via miR-4436a/CTNNB1 ceRNA pathway |
| Pubmed ID | 32239719 |
| Year | 2020 |
| Title | lncRNA SNHG11 Promotes Lung Cancer Cell Proliferation and Migration via Activation of Wnt/?-catenin Signaling Pathway |
External Links
| Links for SNHG11 | GenBank HGNC NONCODE |
| Links for lung cancer | OMIM COSMIC |