Basic Information
| LncRNA/CircRNA Name | SNHG12 |
| Synonyms | NA |
| Region | GRCh38_1:28578538-28582983 |
| Ensemble | ENSG00000197989 |
| Refseq | NR_024127 |
Classification Information
| Regulatory Mechanism | Biological Function | Clinical Application | |||
|---|---|---|---|---|---|
| TF | Immune | Survival | |||
| Enhancer | Apoptosis | apoptosis | Drug | ||
| Variant | Cell Growth | Circulating | |||
| MiRNA | EMT | Metastasis | |||
| Methylation | Coding Ability | Recurrence |
Cancer&Entry Information
| Cancer Name | glioblastoma |
| ICD-0-3 | NA |
| Methods | qRT-PCR, Western blot |
| Sample | GBM tissues,cell lines |
| Expression Pattern | up-regulated |
| Function Description | SNHG12 could serve as a promising therapeutic target to surmount TMZ resistance, thereby improving the clinical efficacy of TMZ chemotherapy. |
| Pubmed ID | 32039732 |
| Year | 2020 |
| Title | DNA-methylation-mediated activating of lncRNA SNHG12 promotes temozolomide resistance in glioblastoma |
External Links
| Links for SNHG12 | GenBank HGNC NONCODE |
| Links for glioblastoma | OMIM COSMIC |