Basic Information
| LncRNA/CircRNA Name | SNHG12 |
| Synonyms | NA |
| Region | GRCh38_1:28578538-28582983 |
| Ensemble | ENSG00000197989 |
| Refseq | NR_024127 |
Classification Information
| Regulatory Mechanism | Biological Function | Clinical Application | |||
|---|---|---|---|---|---|
| TF | Immune | Survival | |||
| Enhancer | Apoptosis | Drug | |||
| Variant | Cell Growth | Circulating | |||
| MiRNA | EMT | Metastasis | |||
| Methylation | Coding Ability | Recurrence |
Cancer&Entry Information
| Cancer Name | osteosarcoma |
| ICD-0-3 | NA |
| Methods | qRT-PCR, Western blot |
| Sample | OS cell lines |
| Expression Pattern | up-regulated |
| Function Description | lncSNHG12 was upregulated in OS cell lines.Downregulation lncSNHG12 suppressed the metastasis and proliferation both in vitro and in vivo. |
| Pubmed ID | 31743769 |
| Year | 2019 |
| Title | Downregulation of lncRNA SNHG12 reversed IGF1R-induced osteosarcoma metastasis and proliferation by targeting miR-195-5p |
External Links
| Links for SNHG12 | GenBank HGNC NONCODE |
| Links for osteosarcoma | OMIM COSMIC |