Basic Information
| LncRNA/CircRNA Name | SNHG15 |
| Synonyms | NA |
| Region | GRCh38_7:44983023-44986961 |
| Ensemble | ENSG00000232956 |
| Refseq | NR_003697 |
Classification Information
| Regulatory Mechanism | Biological Function | Clinical Application | |||
|---|---|---|---|---|---|
| TF | Immune | Survival | |||
| Enhancer | Apoptosis | apoptosis | Drug | ||
| Variant | Cell Growth | Circulating | |||
| MiRNA | EMT | Metastasis | |||
| Methylation | Coding Ability | Recurrence |
Cancer&Entry Information
| Cancer Name | breast cancer |
| ICD-0-3 | C50 |
| Methods | qRT-PCR, RIP |
| Sample | breast cancer tissues,cell Lines |
| Expression Pattern | up-regulated |
| Function Description | SNHG15 was found to be up-regulated in cisplatin resistant breast cancer tissues and cell lines. Breast cancer patients with high SNHG15 expression had a poor prognosis. SNHG15 silencing enhanced cisplatin sensitivity of MCF-7/DDP and MDA-MB-231/DDP cells. Additionally, SNHG15 could function as a miR-381 sponge. |
| Pubmed ID | 32021307 |
| Year | 2020 |
| Title | SNHG15 Contributes To Cisplatin Resistance In Breast Cancer Through Sponging miR-381 |
External Links
| Links for SNHG15 | GenBank HGNC NONCODE |
| Links for breast cancer | OMIM COSMIC |