Basic Information
| LncRNA/CircRNA Name | SNHG15 |
| Synonyms | NA |
| Region | GRCh38_7:44983023-44986961 |
| Ensemble | ENSG00000232956 |
| Refseq | NR_003697 |
Classification Information
| Regulatory Mechanism | Biological Function | Clinical Application | |||
|---|---|---|---|---|---|
| TF | Immune | Survival | |||
| Enhancer | Apoptosis | apoptosis | Drug | ||
| Variant | Cell Growth | Circulating | |||
| MiRNA | EMT | Metastasis | |||
| Methylation | Coding Ability | Recurrence |
Cancer&Entry Information
| Cancer Name | colorectal cancer |
| ICD-0-3 | C19.9 |
| Methods | qPCR, Luciferase reporter assay, Western blot |
| Sample | CRC tissues,cell lines(HCT116, SW620, LoVo, SW480,293T) |
| Expression Pattern | up-regulated |
| Function Description | Researches showed that SNHG15 is overexpressed in gastric cancer (GC), nonsmall cell lung cancer(NSCLC) and breast cancer, and it could promote cell proliferation in these cancers.In this study, we proved that SNHG15 is up-regulated in CRC tissues than the matched noncancerous tissues(NCTs). |
| Pubmed ID | 30945457 |
| Year | 2019 |
| Title | LncRNA-SNHG15 enhances cell proliferation in colorectal cancer by inhibiting miR-338-3p. |
External Links
| Links for SNHG15 | GenBank HGNC NONCODE |
| Links for colorectal cancer | OMIM COSMIC |