Basic Information
LncRNA/CircRNA Name | SNHG15 |
Synonyms | SNHG15, C7orf40, Linc-Myo1g, MYO1GUT |
Region | GRCh38_7:44983023-44986961 |
Ensemble | ENSG00000232956 |
Refseq | NR_003697 |
Classification Information
Regulatory Mechanism | Biological Function | Clinical Application | |||
---|---|---|---|---|---|
TF | Immune | Survival | |||
Enhancer | Apoptosis | Drug | |||
Variant | Cell Growth | Circulating | |||
MiRNA | EMT | Metastasis | |||
Methylation | Coding Ability | Recurrence |
Cancer&Entry Information
Cancer Name | pancreatic cancer |
ICD-0-3 | C25 |
Methods | Western blot, RIP |
Sample | pancreatic cancer tissues, PC cell lines. |
Expression Pattern | up-regulated |
Function Description | Our results reported that SNHG15 could act as an oncogene in PC, revealing its potential value as a biomarker for early detection and individualized therapy.Compared with the steadily increasing survival rates in some cancers, colorectal cancer is characterized by a poor prognosis, which limits the 5-year relative survival to only 8 %. |
Pubmed ID | 29137412 |
Year | 2017 |
Title | Long non-coding RNA SNHG15 inhibits P15 and KLF2 expression to promote pancreatic cancer proliferation through EZH2-mediated H3K27me3 |
External Links
Links for SNHG15 | GenBank HGNC NONCODE |
Links for pancreatic cancer | OMIM COSMIC |