Basic Information
| LncRNA/CircRNA Name | SNHG18 |
| Synonyms | NA |
| Region | GRCh38_5:9546200-9550609 |
| Ensemble | ENSG00000250786 |
| Refseq | NR_045196 |
Classification Information
| Regulatory Mechanism | Biological Function | Clinical Application | |||
|---|---|---|---|---|---|
| TF | Immune | Survival | |||
| Enhancer | Apoptosis | Drug | |||
| Variant | Cell Growth | Circulating | |||
| MiRNA | EMT | Metastasis | |||
| Methylation | Coding Ability | Recurrence |
Cancer&Entry Information
| Cancer Name | glioma |
| ICD-0-3 | NA |
| Methods | qPCR, Western blot etc |
| Sample | cell lines(M059J and M059K) |
| Expression Pattern | differential expressed |
| Function Description | In the present study, we showed that SNHG18 promoted the invasion and migration of glioma cells. SNHG18 was demonstrated to regulate the progression of epithelial-mesenchymal transition and cytoskeleton remodeling, thereby affecting cell motility. Furthermore, the promotion of invasion evoked by SNHG18 overexpression could be rescued by ?-enolase (ENO1) deletion. |
| Pubmed ID | 31798634 |
| Year | 2019 |
| Title | Long Noncoding Ribonucleic Acid SNHG18 Promotes Glioma Cell Motility via Disruption of ?-Enolase Nucleocytoplasmic Transport |
External Links
| Links for SNHG18 | GenBank HGNC NONCODE |
| Links for glioma | OMIM COSMIC |