Basic Information
| LncRNA/CircRNA Name | SNHG20 |
| Synonyms | SNHG20, C17orf86, LINC00338, NCRNA00338, SCARNA16HG |
| Region | GRCh38_17:77086716-77094990 |
| Ensemble | ENSG00000234912 |
| Refseq | NR_027058 |
Classification Information
| Regulatory Mechanism | Biological Function | Clinical Application | |||
|---|---|---|---|---|---|
| TF | Immune | Survival | |||
| Enhancer | Apoptosis | Drug | |||
| Variant | Cell Growth | Circulating | |||
| MiRNA | EMT | Metastasis | |||
| Methylation | Coding Ability | Recurrence |
Cancer&Entry Information
| Cancer Name | ovarian cancer |
| ICD-0-3 | C56.9 |
| Methods | qPCR, Western blot, in vitro knockdown, RNAi |
| Sample | ovarian cancer tissues, ovarian cancer cell lines (SKOV3, OVCA429, OVCA433 and OVCAR3) |
| Expression Pattern | up-regulated |
| Function Description | lncRNA SNHG20 was significantly increased in ovarian cancer.lncRNA SNHG20 knockdown inhibited Wnt/B-catenin signaling activity by suppressing B-catenin expression and reversing the downstream target gene expression. |
| Pubmed ID | 29101241 |
| Year | 2018 |
| Title | Up-regulation of long non-coding RNA SNHG20 promotes ovarian cancer progression via Wnt/B-catenin signaling. |
External Links
| Links for SNHG20 | GenBank HGNC NONCODE |
| Links for ovarian cancer | OMIM COSMIC |