Basic Information
| LncRNA/CircRNA Name | C2dat1 |
| Synonyms | NA |
| Region | NA |
| Ensemble | NA |
| Refseq | NA |
Classification Information
| Regulatory Mechanism | Biological Function | Clinical Application | |||
|---|---|---|---|---|---|
| TF | Immune | Survival | |||
| Enhancer | Apoptosis | Drug | |||
| Variant | Cell Growth | Circulating | |||
| MiRNA | EMT | Metastasis | |||
| Methylation | Coding Ability | Recurrence |
Cancer&Entry Information
| Cancer Name | osteosarcoma |
| ICD-0-3 | NA |
| Methods | Luciferase Reporter Assay , qPCR, Western blot etc. |
| Sample | cell lines (MG63, OS-732, hFOB1.19) |
| Expression Pattern | differential expression |
| Function Description | C2dat1 suppression reduced cell viability,invasion and migration,while increased cell apoptosis in OS-732 cells. MiR-34a-5p was a target of C2dat1. |
| Pubmed ID | 28810936 |
| Year | 2017 |
| Title | LncRNA C2dat1 Promotes Cell Proliferation, Migration, and Invasion by Targeting MiR-34a-5p in Osteosarcoma Cells. |
External Links
| Links for C2dat1 | GenBank HGNC NONCODE |
| Links for osteosarcoma | OMIM COSMIC |