Basic Information
| LncRNA/CircRNA Name | SNHG7 |
| Synonyms | NA |
| Region | GRCh38_9:136721366-136728184 |
| Ensemble | ENSG00000233016 |
| Refseq | NR_003672 |
Classification Information
| Regulatory Mechanism | Biological Function | Clinical Application | |||
|---|---|---|---|---|---|
| TF | Immune | Survival | |||
| Enhancer | Apoptosis | Drug | |||
| Variant | Cell Growth | Circulating | |||
| MiRNA | EMT | Metastasis | |||
| Methylation | Coding Ability | Recurrence |
Cancer&Entry Information
| Cancer Name | nasopharyngeal cancer |
| ICD-0-3 | C11 |
| Methods | qPCR, Western blot etc |
| Sample | NPC tissues ,cell line (NP69, 5-8F, 6-18B, CNE1 and CNE2) |
| Expression Pattern | up-regulated |
| Function Description | The role of SNHG7 in the metastasis of NPC was detected through scratch wound assay and Transwell assay. RT-qPCR and western blot assay were used to discover the function of SNHG7 in epithelial-to-mesenchymal transition (EMT) process. Tumor metastasis assay was also performed in vivo. In this study, RT-qPCR results showed that SNHG7 expression in NPC samples was remarkably higher when compared with that in adjacent ones. |
| Pubmed ID | 32218823 |
| Year | 2020 |
| Title | lncRNA SNHG7 Promotes Tumorigenesis of Nasopharyngeal Carcinoma via Epithelial-To-Mesenchymal Transition |
External Links
| Links for SNHG7 | GenBank HGNC NONCODE |
| Links for nasopharyngeal cancer | OMIM COSMIC |