Basic Information
| LncRNA/CircRNA Name | SNHG7 |
| Synonyms | Small nucleolar RNA host gene 7 |
| Region | GRCh38_9:136721366-136728184 |
| Ensemble | ENSG00000233016 |
| Refseq | NR_003672 |
Classification Information
| Regulatory Mechanism | Biological Function | Clinical Application | |||
|---|---|---|---|---|---|
| TF | Immune | Survival | |||
| Enhancer | Apoptosis | apoptosis | Drug | ||
| Variant | Cell Growth | Circulating | |||
| MiRNA | EMT | Metastasis | |||
| Methylation | Coding Ability | Recurrence |
Cancer&Entry Information
| Cancer Name | renal cell carcinoma |
| ICD-0-3 | C64.9 |
| Methods | RT-qPCR, Western blot analysis |
| Sample | Caki-1,769-P,786-O,and ACHN RCC cell lines,a normal human kidney epithelial cell (HK2) and 293T cell,RCC tissues |
| Expression Pattern | up-regulated |
| Function Description | SNHG7 expression was remarkably upregulated in tumor tissues when compared with adjacent tissues. Moreover, RCC cell proliferation was inhibited and cell apoptosis was promoted after knockdown of SNHG7 in vitro. Moreover, after knockdown of SNHG7, CDKN1A was upregulated at mRNA and protein level in vitro. |
| Pubmed ID | 31841178 |
| Year | 2019 |
| Title | LncRNA SNHG7 Promotes the Proliferation and Inhibits Apoptosis of Renal Cell Cancer Cells by Downregulating CDKN1A |
External Links
| Links for SNHG7 | GenBank HGNC NONCODE |
| Links for renal cell carcinoma | OMIM COSMIC |