Basic Information
| LncRNA/CircRNA Name | SNHG7 |
| Synonyms | NA |
| Region | GRCh38_9:136721366-136728184 |
| Ensemble | ENSG00000233016 |
| Refseq | NR_003672 |
Classification Information
| Regulatory Mechanism | Biological Function | Clinical Application | |||
|---|---|---|---|---|---|
| TF | Immune | Survival | |||
| Enhancer | Apoptosis | Drug | |||
| Variant | Cell Growth | Circulating | |||
| MiRNA | EMT | Metastasis | |||
| Methylation | Coding Ability | Recurrence |
Cancer&Entry Information
| Cancer Name | thyroid cancer |
| ICD-0-3 | C73.9 |
| Methods | qRT-PCR , in vitro knockdown etc. |
| Sample | thyroid carcinoma CAL62 and thyroid gland squamous SW579 carcinoma cell lines |
| Expression Pattern | up-regulated |
| Function Description | SNHG7 is markedly upregulated in THCA samples .SNHG7 expression was higher in advanced stage compared with early stage THCA samples. In addition, high expression levels of SNHG7 were associated with shorter survival times in THCA patients compared with low expression levels.Additionally, knockdown of SNHG7 significantly inhibited thyroid cancer cell proliferation and cell cycle progression in vitro. |
| Pubmed ID | 31611982 |
| Year | 2019 |
| Title | Long Non-Coding RNA Small Nucleolar RNA Host Gene 7 Is Upregulated and Promotes Cell Proliferation in Thyroid Cancer |
External Links
| Links for SNHG7 | GenBank HGNC NONCODE |
| Links for thyroid cancer | OMIM COSMIC |