Basic Information
| LncRNA/CircRNA Name | SNHG7 |
| Synonyms | SNHG7, NCRNA00061 |
| Region | GRCh38_9:136721366-136728184 |
| Ensemble | ENSG00000233016 |
| Refseq | NR_003672 |
Classification Information
| Regulatory Mechanism | Biological Function | Clinical Application | |||
|---|---|---|---|---|---|
| TF | Immune | Survival | |||
| Enhancer | Apoptosis | apoptosis | Drug | ||
| Variant | Cell Growth | Circulating | |||
| MiRNA | EMT | Metastasis | |||
| Methylation | Coding Ability | Recurrence |
Cancer&Entry Information
| Cancer Name | bladder cancer |
| ICD-0-3 | C67 |
| Methods | qRT-PCR ect. |
| Sample | Bladder cancer cell lines (T24, J82 and SW780) and normal human bladder cell line (SV-HUC-1), Surgical bladder cancer tissues matched near-cancer tissues |
| Expression Pattern | up-regulated |
| Function Description | lncRNA-SNHG7 was upregulated in bladder cancer cell lines. After the expression of lncRNA-SNHG7 was downregulated, the proliferation of bladder cancer cells was decreased, the apoptosis was increased, and the invasion ability of cells was decreased. The expression of E-cadherin was increased, but the expression of N-cadherin, vimentin and snail were decreased. Increased expression of lncRNASNHG7 in cancer tissues was significantly related to tumor size, metastasis and stage. |
| Pubmed ID | 30003751 |
| Year | 2018 |
| Title | LncRNA-SNHG7 regulates proliferation, apoptosis and invasion of bladder cancer cells assurance guidelines. |
External Links
| Links for SNHG7 | GenBank HGNC NONCODE |
| Links for bladder cancer | OMIM COSMIC |