Basic Information
| LncRNA/CircRNA Name | SNHG7 |
| Synonyms | SNHG7, NCRNA00061 |
| Region | GRCh38_9:136721366-136728184 |
| Ensemble | ENSG00000233016 |
| Refseq | NR_003672 |
Classification Information
| Regulatory Mechanism | Biological Function | Clinical Application | |||
|---|---|---|---|---|---|
| TF | Immune | Survival | |||
| Enhancer | Apoptosis | Drug | |||
| Variant | Cell Growth | Circulating | |||
| MiRNA | EMT | Metastasis | |||
| Methylation | Coding Ability | Recurrence |
Cancer&Entry Information
| Cancer Name | colorectal cancer |
| ICD-0-3 | C19.9 |
| Methods | qPCR, Western blot, Dual luciferase reporter assays, RIP, etc. |
| Sample | colorectal cancer tissues, cell lines (SW480, SW620, LOVO, HCT-116, FHC) |
| Expression Pattern | up-regulated |
| Function Description | SNHG7 overexpression promoted the proliferation, migration, and invasion of CRC cell lines. SNHG7 directly interacted with miR-216b and downregulation of miR-216b reversed efficiently the suppression of GALNT1 induced by SNHG7 siRNA. Kaplan?Meier survival analysis showed that high expression of SNHG7 was associated with CRC poor overall survival. |
| Pubmed ID | 29915311 |
| Year | 2018 |
| Title | LncRNA SNHG7 sponges miR-216b to promote proliferation and liver metastasis of colorectal cancer through upregulating GALNT1. |
External Links
| Links for SNHG7 | GenBank HGNC NONCODE |
| Links for colorectal cancer | OMIM COSMIC |