Basic Information
| LncRNA/CircRNA Name | SNHG9 |
| Synonyms | NA |
| Region | GRCh38_16:1964959-1965509 |
| Ensemble | ENSG00000255198 |
| Refseq | NR_003142 |
Classification Information
| Regulatory Mechanism | Biological Function | Clinical Application | |||
|---|---|---|---|---|---|
| TF | Immune | Survival | |||
| Enhancer | Apoptosis | apoptosis | Drug | ||
| Variant | Cell Growth | Circulating | |||
| MiRNA | EMT | Metastasis | |||
| Methylation | Coding Ability | Recurrence |
Cancer&Entry Information
| Cancer Name | glioblastoma |
| ICD-0-3 | NA |
| Methods | qPCR, Luciferase reporter assay, etc. |
| Sample | Glioma tissues, glioma cell lines (H4, T98G, LN229, U87, U251, SW1783),Normal human astrocytes (NHAs) |
| Expression Pattern | up-regulated |
| Function Description | mRNA expression of SNHG9 was elevated in glioblastoma tissues. The elevated SNHG9 expression was related to lower survival rate in patients with glioma. SNHG9 could downregulate miR-199a-5p and upregulate Wnt2 in glioblastoma cells. Overexpression of SNHG9 in glioblastoma cells promoted aerobic glycolysis and cell proliferation, which could be attenuated by miR-199a-5p. |
| Pubmed ID | 31504670 |
| Year | 2019 |
| Title | SNHG9/miR-199a-5p/Wnt2 Axis Regulates Cell Growth and Aerobic Glycolysis in Glioblastoma |
External Links
| Links for SNHG9 | GenBank HGNC NONCODE |
| Links for glioblastoma | OMIM COSMIC |