Basic Information
| LncRNA/CircRNA Name | sONE |
| Synonyms | NA |
| Region | NA |
| Ensemble | NA |
| Refseq | NA |
Classification Information
| Regulatory Mechanism | Biological Function | Clinical Application | |||
|---|---|---|---|---|---|
| TF | Immune | Survival | |||
| Enhancer | Apoptosis | Drug | |||
| Variant | Cell Growth | Circulating | |||
| MiRNA | EMT | Metastasis | |||
| Methylation | Coding Ability | Recurrence |
Cancer&Entry Information
| Cancer Name | breast cancer |
| ICD-0-3 | C50 |
| Methods | qPCR, Western blot |
| Sample | BC tissues and cell lines(MDA-MB-231) |
| Expression Pattern | down-regulated |
| Function Description | this study highlights sONE as a downregulated tumor suppressor lncRNA in TNBC cells acting through repressing eNOS-induced NO production |
| Pubmed ID | 30968427 |
| Year | 2019 |
| Title | The long noncoding RNA sONE represses triple-negative breast cancer aggressiveness through inducing the expression of miR-34a, miR-15a, miR -16, and let-7a. |
External Links
| Links for sONE | GenBank HGNC NONCODE |
| Links for breast cancer | OMIM COSMIC |