Basic Information
| LncRNA/CircRNA Name | SOX2OT |
| Synonyms | SOX2-OT, NCRNA00043, SOX2OT |
| Region | GRCh38_3:180989762-181836880 |
| Ensemble | ENSG00000242808 |
| Refseq | NR_004053 |
Classification Information
| Regulatory Mechanism | Biological Function | Clinical Application | |||
|---|---|---|---|---|---|
| TF | Immune | Survival | |||
| Enhancer | Apoptosis | Drug | |||
| Variant | Cell Growth | Circulating | |||
| MiRNA | EMT | Metastasis | |||
| Methylation | Coding Ability | Recurrence |
Cancer&Entry Information
| Cancer Name | hepatocellular carcinoma |
| ICD-0-3 | C22.0 |
| Methods | qPCR, RNAi etc. |
| Sample | HCC tissues, cell lines (HepG2, SMMC-7721) |
| Expression Pattern | up-regulated |
| Function Description | lncRNA Sox2ot expression level was significantly higher in HCC tissues compared with adjacent non-tumor tissues. High expression of lncRNA Sox2ot was associated with histological grade, TNM stage, and vein invasion. |
| Pubmed ID | 26097588 |
| Year | 2015 |
| Title | Up-regulation of long non-coding RNA Sox2ot promotes hepatocellular carcinoma cell metastasis and correlates with poor prognosis. |
External Links
| Links for SOX2OT | GenBank HGNC NONCODE |
| Links for hepatocellular carcinoma | OMIM COSMIC |