Basic Information
| LncRNA/CircRNA Name | CAHM |
| Synonyms | CAHM, LINC00468 |
| Region | GRCh38_6:163413065-163413960 |
| Ensemble | ENSG00000270419 |
| Refseq | NR_037593 |
Classification Information
| Regulatory Mechanism | Biological Function | Clinical Application | |||
|---|---|---|---|---|---|
| TF | Immune | Survival | |||
| Enhancer | Apoptosis | apoptosis | Drug | ||
| Variant | Cell Growth | Circulating | |||
| MiRNA | EMT | Metastasis | |||
| Methylation | Coding Ability | Recurrence |
Cancer&Entry Information
| Cancer Name | colorectal cancer |
| ICD-0-3 | C19.9 |
| Methods | qPCR, MSP-PCR etc. |
| Sample | blood, CRC tissues |
| Expression Pattern | down-regulated |
| Function Description | A reverse transcriptase-qPCR assay showed that CAHM RNA levels correlated negatively with CAHM % methylation, and therefore CAHM gene expression is typically decreased in CRC. Both the frequency of detection and the amount of methylated CAHM DNA released into plasma increased with increasing cancer stage. |
| Pubmed ID | 24799664 |
| Year | 2014 |
| Title | CAHM, a long non-coding RNA gene hypermethylated in colorectal neoplasia. |
External Links
| Links for CAHM | GenBank HGNC NONCODE |
| Links for colorectal cancer | OMIM COSMIC |