Basic Information
| LncRNA/CircRNA Name | SPRY4-IT1 |
| Synonyms | SPRY4-IT1, SPRIGHTLY |
| Region | NA |
| Ensemble | ENSG00000281881 |
| Refseq | NR_131221 |
Classification Information
| Regulatory Mechanism | Biological Function | Clinical Application | |||
|---|---|---|---|---|---|
| TF | Immune | Survival | |||
| Enhancer | Apoptosis | Drug | |||
| Variant | Cell Growth | Circulating | |||
| MiRNA | EMT | Metastasis | |||
| Methylation | Coding Ability | Recurrence |
Cancer&Entry Information
| Cancer Name | hepatocellular carcinoma |
| ICD-0-3 | C22.0 |
| Methods | qPCR etc. |
| Sample | blood, cell lines (Hep-3B, HepG2, HuH-7 etc.) |
| Expression Pattern | up-regulated |
| Function Description | In the present study, we focused on the expression pattern of lncRNA SPRY4 intronic transcript 1 (SPRY4-IT1) and its clinical significance in HCC diagnostics. The levels of SPRY4-IT1 were upregulated in HCC and were associated with tumor differentiation, tumor size and tumor-node-metastasis (TNM) stage. |
| Pubmed ID | 27278245 |
| Year | 2016 |
| Title | Potential diagnostic value of lncRNA SPRY4-IT1 in hepatocellular carcinoma. |
External Links
| Links for SPRY4-IT1 | GenBank HGNC NONCODE |
| Links for hepatocellular carcinoma | OMIM COSMIC |