Basic Information
| LncRNA/CircRNA Name | SPRY4-IT1 |
| Synonyms | SPRY4-IT1, SPRIGHTLY |
| Region | NA |
| Ensemble | ENSG00000281881 |
| Refseq | NR_131221 |
Classification Information
| Regulatory Mechanism | Biological Function | Clinical Application | |||
|---|---|---|---|---|---|
| TF | Immune | Survival | |||
| Enhancer | Apoptosis | Drug | |||
| Variant | Cell Growth | Circulating | |||
| MiRNA | EMT | Metastasis | |||
| Methylation | Coding Ability | Recurrence |
Cancer&Entry Information
| Cancer Name | glioma |
| ICD-0-3 | NA |
| Methods | qPCR etc. |
| Sample | glioma tissues |
| Expression Pattern | up-regulated |
| Function Description | The expression level of SPRY4-IT1 was significantly higher in glioma in comparison to normal matched tissue. Furthermore, lncRNA SPRY4-IT1 was associated significantly with WHO grade and tumor size. A significant difference was found that glioma patients with high SPRY4-IT1 expression level had distinctly shorter OS than patients with low SPRY4-IT1 expression level. |
| Pubmed ID | 27460732 |
| Year | 2016 |
| Title | Long noncoding RNA SPRY4-IT1 is a prognostic factor for poor overall survival and has an oncogenic role in glioma. |
External Links
| Links for SPRY4-IT1 | GenBank HGNC NONCODE |
| Links for glioma | OMIM COSMIC |