Basic Information
| LncRNA/CircRNA Name | ST8SIA6-AS1 |
| Synonyms | STAR1 |
| Region | GRCh38_10:17386936-17413503 |
| Ensemble | ENSG00000204832 |
| Refseq | NR_034129 |
Classification Information
| Regulatory Mechanism | Biological Function | Clinical Application | |||
|---|---|---|---|---|---|
| TF | Immune | Survival | |||
| Enhancer | Apoptosis | apoptosis | Drug | ||
| Variant | Cell Growth | Circulating | |||
| MiRNA | EMT | Metastasis | |||
| Methylation | Coding Ability | Recurrence |
Cancer&Entry Information
| Cancer Name | breast cancer |
| ICD-0-3 | C50 |
| Methods | qPCR |
| Sample | cell lines (MCF-10A, MCF-12A, MDA-MB-231, MCF-7) |
| Expression Pattern | up-regulated |
| Function Description | KLHDC7B and STAR1 are both overexpressed in breast cancer. STAR1, however, suppressed cell migration and increased apoptosis. KLHDC7B and STAR1 show opposite activity in cancer cell proliferation. |
| Pubmed ID | 30150751 |
| Year | 2018 |
| Title | A Kelch domain-containing KLHDC7B and a long non-coding RNA ST8SIA6-AS1 act oppositely on breast cancer cell proliferation via the interferon signaling pathway. |
External Links
| Links for ST8SIA6-AS1 | GenBank HGNC NONCODE |
| Links for breast cancer | OMIM COSMIC |