Basic Information
| LncRNA/CircRNA Name | STARD13-AS |
| Synonyms | NA |
| Region | GRCh38_13:33180401-33281584 |
| Ensemble | ENSG00000236581 |
| Refseq | NR_046693 |
Classification Information
| Regulatory Mechanism | Biological Function | Clinical Application | |||
|---|---|---|---|---|---|
| TF | Immune | Survival | |||
| Enhancer | Apoptosis | apoptosis | Drug | ||
| Variant | Cell Growth | Circulating | |||
| MiRNA | EMT | Metastasis | |||
| Methylation | Coding Ability | Recurrence |
Cancer&Entry Information
| Cancer Name | colorectal cancer |
| ICD-0-3 | C19.9 |
| Methods | qRT-PCR, Western blotting |
| Sample | CRC tissue samples,colon mucosal epithelial cell line NCM460 and the human CRC cell lines LoVo, RKO, HCT-116, HT-29, SW620, and SW480 |
| Expression Pattern | down-regulated |
| Function Description | STARD13-AS expression was decreased in CRC tissues.while STARD13-AS overexpression suppressed the cell cycle, proliferation, migration, and invasion, while promoted apoptosis both in LoVo and SW620 cells. In addition, STARD13-AS overexpression inhibited Cyclin E, Cyclin D, N-cadherin and vimentin expression, and promoted E-cadherin expression both in LoVo and SW620 cells. |
| Pubmed ID | 31807011 |
| Year | 2019 |
| Title | Long Non-Coding RNA STARD13-AS Suppresses Cell Proliferation And Metastasis In Colorectal Cancer |
External Links
| Links for STARD13-AS | GenBank HGNC NONCODE |
| Links for colorectal cancer | OMIM COSMIC |