Basic Information
| LncRNA/CircRNA Name | STCAT3 |
| Synonyms | NA |
| Region | NA |
| Ensemble | NA |
| Refseq | NA |
Classification Information
| Regulatory Mechanism | Biological Function | Clinical Application | |||
|---|---|---|---|---|---|
| TF | Immune | Survival | |||
| Enhancer | Apoptosis | Drug | |||
| Variant | Cell Growth | Circulating | |||
| MiRNA | EMT | Metastasis | |||
| Methylation | Coding Ability | Recurrence |
Cancer&Entry Information
| Cancer Name | gastric cancer |
| ICD-0-3 | C16 |
| Methods | qPCR, Cell migration and invasion assay etc. |
| Sample | gastric cancer tissues, cell lines (SGC-7901, MKN-45, AGS, MGC-803, BGC-823, MKN-28) |
| Expression Pattern | up-regulated |
| Function Description | The expression of lncRNA STCAT3 was generally up-regulated in gastric cancer tissues compared with the adjacent tissues(12.55?0.16 vs 6.52?0.14), with median expression level in gastric cancer tissues being 6.03 higher. Meanwhile, the expression level of lncRNA STCAT3 in gastric cancer tissues was not correlated with age or gender, while positively correlated with TNM stage. Interference of lncRNA STCAT3 expression in BGC-823 cells was found associated with significantly suppressed colony formation, proliferation, invasion, and migration. Over-expression of lncRNA STCAT3 in AGS cells were also founded could promote the gastric cancer cells' proliferation, colony formation, migration, and invasio |
| Pubmed ID | 27998431 |
| Year | 2017 |
| Title | Expression of long noncoding RNA STCAT3 in gastric cancer tissues and its effect on malignant phenotype of gastric cancer cells. |
External Links
| Links for STCAT3 | GenBank HGNC NONCODE |
| Links for gastric cancer | OMIM COSMIC |