Basic Information
| LncRNA/CircRNA Name | SUMO1P3 |
| Synonyms | NA |
| Region | GRCh38_1:160317403-160317706 |
| Ensemble | ENSG00000235082 |
| Refseq | NA |
Classification Information
| Regulatory Mechanism | Biological Function | Clinical Application | |||
|---|---|---|---|---|---|
| TF | Immune | Survival | |||
| Enhancer | Apoptosis | Drug | |||
| Variant | Cell Growth | Circulating | |||
| MiRNA | EMT | Metastasis | |||
| Methylation | Coding Ability | Recurrence |
Cancer&Entry Information
| Cancer Name | hepatocellular carcinoma |
| ICD-0-3 | C22.0 |
| Methods | qRT-PCR, Western blot, Luciferase reporter assay |
| Sample | Hepatocellular carcinoma tissues,cell lines(HepG2 and THLE3) |
| Expression Pattern | up-regulated |
| Function Description | Elevated expression of SUMO1P3 predicts malignant progression among HCC patients. SUMO1P3 enhances Wnt/?-catenin pathway through sponging miR-320a, thus contributing to aggressive progression of HCC.SUMO1P3 promotes tumorigenesis through regulating epithelial-mesenchymal transition (EMT) signalling pathway and angiogenesis. |
| Pubmed ID | 31970876 |
| Year | 2020 |
| Title | Long non-coding RNA SUMO1P3 promotes hepatocellular carcinoma progression through activating Wnt/?-catenin signalling pathway by targeting miR-320a |
External Links
| Links for SUMO1P3 | GenBank HGNC NONCODE |
| Links for hepatocellular carcinoma | OMIM COSMIC |