Basic Information
| LncRNA/CircRNA Name | CAR10 |
| Synonyms | ADAM12, ADAM12-OT1, CAR10, MCMP, MCMPMltna, MLTN, MLTNA |
| Region | GRCh38_10:126012381-126388455 |
| Ensemble | ENSG00000148848 |
| Refseq | NA |
Classification Information
| Regulatory Mechanism | Biological Function | Clinical Application | |||
|---|---|---|---|---|---|
| TF | Immune | Survival | |||
| Enhancer | Apoptosis | Drug | |||
| Variant | Cell Growth | Circulating | |||
| MiRNA | EMT | Metastasis | |||
| Methylation | Coding Ability | Recurrence |
Cancer&Entry Information
| Cancer Name | non small cell lung cancer |
| ICD-0-3 | C34 |
| Methods | qPCR etc. |
| Sample | NSCLC tissues |
| Expression Pattern | up-regulated |
| Function Description | To identify lncRNAs that are critical to lung carcinogenesis, we selected three lncRNAs, CAR intergenic 10 (hereafter, CAR10), AK311218, and RP11-480I12.3, from the most up-regulated lncRNAs in the HPR NSCLCs (Table S3) and tested their expression by quantitative reverse transcription polymerase chain reaction (qRT-PCR). The expression of these lncRNAs was consistent with the microarray analysis. |
| Pubmed ID | 27322209 |
| Year | 2016 |
| Title | Long non-coding RNA stabilizes the Y-box-binding protein 1 and regulates the epidermal growth factor receptor to promote lung carcinogenesis. |
External Links
| Links for CAR10 | GenBank HGNC NONCODE |
| Links for non small cell lung cancer | OMIM COSMIC |