Basic Information
| LncRNA/CircRNA Name | CARLo-5 |
| Synonyms | CCAT1, CARLo-5, onco-lncRNA-40 |
| Region | GRCh38_8:127207382-127219268 |
| Ensemble | ENSG00000247844 |
| Refseq | NR_108049 |
Classification Information
| Regulatory Mechanism | Biological Function | Clinical Application | |||
|---|---|---|---|---|---|
| TF | Immune | Survival | |||
| Enhancer | Apoptosis | Drug | |||
| Variant | Cell Growth | Circulating | |||
| MiRNA | EMT | Metastasis | |||
| Methylation | Coding Ability | Recurrence |
Cancer&Entry Information
| Cancer Name | endometrial cancer |
| ICD-0-3 | NA |
| Methods | qPCR etc. |
| Sample | EC tissues |
| Expression Pattern | up-regulated |
| Function Description | CARLo-5 expression was significantly higher in EC tissues than in NETs and significantly associated with FIGO stage and lymph node metastasis. Patients with high CARLo-5 expression had significantly shorter overall survival than those with low CARLo-5 expression. The rs6983267 genotype was significantly correlated with CARLo-5 expression. |
| Pubmed ID | 27432114 |
| Year | 2016 |
| Title | The rs6983267 SNP and long non-coding RNA CARLo-5 are associated with endometrial carcinoma. |
External Links
| Links for CARLo-5 | GenBank HGNC NONCODE |
| Links for endometrial cancer | OMIM COSMIC |