Basic Information
| LncRNA/CircRNA Name | TDRG1 |
| Synonyms | NA |
| Region | GRCh38_6:40334954-40379887 |
| Ensemble | ENSG00000204091 |
| Refseq | NA |
Classification Information
| Regulatory Mechanism | Biological Function | Clinical Application | |||
|---|---|---|---|---|---|
| TF | Immune | Survival | |||
| Enhancer | Apoptosis | Drug | |||
| Variant | Cell Growth | Circulating | |||
| MiRNA | EMT | Metastasis | |||
| Methylation | Coding Ability | Recurrence |
Cancer&Entry Information
| Cancer Name | gastric cancer |
| ICD-0-3 | C16 |
| Methods | qRT-PCR, RIP |
| Sample | GC tissues,cell lines |
| Expression Pattern | up-regulated |
| Function Description | lncRNA testis development-related gene 1 (TDRG1) is markedly upregulated in clinical GC tissues and GC cells.Overexpression of lncRNA TDRG1 promotes GC growth and metastatic-related traits in vitro and in vivo, and silencing TDRG1 causes opposite results. |
| Pubmed ID | 31726370 |
| Year | 2020 |
| Title | LncRNA TDRG1 promotes the aggressiveness of gastric carcinoma through regulating miR-873-5p/HDGF axis |
External Links
| Links for TDRG1 | GenBank HGNC NONCODE |
| Links for gastric cancer | OMIM COSMIC |