Basic Information
| LncRNA/CircRNA Name | TFPI2AS1 |
| Synonyms | NA |
| Region | NA |
| Ensemble | NA |
| Refseq | NA |
Classification Information
| Regulatory Mechanism | Biological Function | Clinical Application | |||
|---|---|---|---|---|---|
| TF | Immune | Survival | |||
| Enhancer | Apoptosis | Drug | |||
| Variant | Cell Growth | Circulating | |||
| MiRNA | EMT | Metastasis | |||
| Methylation | Coding Ability | Recurrence |
Cancer&Entry Information
| Cancer Name | lung cancer |
| ICD-0-3 | C34 |
| Methods | Microarray, qPCR, Western blot |
| Sample | lung cancer tissues, cell line (A549) |
| Expression Pattern | up-regulated |
| Function Description | Among the dysregulated lncRNAs, we identified TFPI2AS1, an antisense transcript of the tumor suppressor TFPI2 (tissue factor pathway inhibitor 2). TFPI2AS1 was shown to be markedly upregulated in NSCLC patient tumors as compared to paired nontumor samples |
| Pubmed ID | 28933981 |
| Year | 2017 |
| Title | TFPI2AS1, a novel lncRNA that inhibits cell proliferation and migration in lung cancer |
External Links
| Links for TFPI2AS1 | GenBank HGNC NONCODE |
| Links for lung cancer | OMIM COSMIC |