Basic Information
| LncRNA/CircRNA Name | TINCR |
| Synonyms | TINCR, LINC00036, NCRNA00036, PLAC2, onco-lncRNA-16 |
| Region | GRCh38_19:5558167-5578349 |
| Ensemble | ENSG00000223573 |
| Refseq | NA |
Classification Information
| Regulatory Mechanism | Biological Function | Clinical Application | |||
|---|---|---|---|---|---|
| TF | Immune | Survival | |||
| Enhancer | Apoptosis | Drug | |||
| Variant | Cell Growth | Circulating | |||
| MiRNA | EMT | Metastasis | |||
| Methylation | Coding Ability | Recurrence |
Cancer&Entry Information
| Cancer Name | gastric cancer |
| ICD-0-3 | C16 |
| Methods | qPCR |
| Sample | gastric cancer tissues |
| Expression Pattern | up-regulated |
| Function Description | Our previous study identified a lncRNA, TINCR, promotes GC proliferation and overexpression of TINCR indicates worse prognosis of GC. The results suggested that E2F1 participate in TINCR transcription regulation. |
| Pubmed ID | 28569791 |
| Year | 2017 |
| Title | E2F1 induces TINCR transcriptional activity and accelerates gastric cancer progression via activation of TINCR/STAU1/CDKN2B signaling axis |
External Links
| Links for TINCR | GenBank HGNC NONCODE |
| Links for gastric cancer | OMIM COSMIC |