Basic Information
| LncRNA/CircRNA Name | TMPO-AS1 |
| Synonyms | NA |
| Region | GRCh38_12:98512973-98516422 |
| Ensemble | ENSG00000257167 |
| Refseq | NR_027157 |
Classification Information
| Regulatory Mechanism | Biological Function | Clinical Application | |||
|---|---|---|---|---|---|
| TF | Immune | Survival | |||
| Enhancer | Apoptosis | Drug | |||
| Variant | Cell Growth | Circulating | |||
| MiRNA | EMT | Metastasis | |||
| Methylation | Coding Ability | Recurrence |
Cancer&Entry Information
| Cancer Name | retinoblastoma |
| ICD-0-3 | C69.2 |
| Methods | qRT-PCR, Western blot |
| Sample | RB tissues,cell lines |
| Expression Pattern | up-regulated |
| Function Description | TMPO-AS1 is abnormally up-regulated in RB tissues, and it can modulate the proliferation and migration of RB cells. It has the potential to be the ??eRNA??to regulate HIF-1? expression by sponging miR-199a-5p. |
| Pubmed ID | 32139259 |
| Year | 2020 |
| Title | LncRNA TMPO-AS1 up-regulates the expression of HIF-1? and promotes the malignant phenotypes of retinoblastoma cells via sponging miR-199a-5p |
External Links
| Links for TMPO-AS1 | GenBank HGNC NONCODE |
| Links for retinoblastoma | OMIM COSMIC |