Basic Information
| LncRNA/CircRNA Name | TMPO-AS1 |
| Synonyms | NA |
| Region | GRCh38_12:98512973-98516422 |
| Ensemble | ENSG00000257167 |
| Refseq | NR_027157 |
Classification Information
| Regulatory Mechanism | Biological Function | Clinical Application | |||
|---|---|---|---|---|---|
| TF | Immune | Survival | |||
| Enhancer | Apoptosis | apoptosis | Drug | ||
| Variant | Cell Growth | Circulating | |||
| MiRNA | EMT | Metastasis | |||
| Methylation | Coding Ability | Recurrence |
Cancer&Entry Information
| Cancer Name | bladder cancer |
| ICD-0-3 | C67 |
| Methods | qRT-PCR, RIP |
| Sample | BCa tissues,cell lines |
| Expression Pattern | up-regulated |
| Function Description | TMPO-AS1 facilitated cell growth. Additionally, TMPO-AS1 also boosted the migration and invasion of BCa cells. Mechanistically, overexpressed EBF transcription factor 1 (EBF1) in BCa cell was verified to promote the transcription of TMPO-AS1. |
| Pubmed ID | 32087328 |
| Year | 2020 |
| Title | TMPO-AS1/miR-98-5p/EBF1 feedback loop contributes to the progression of bladder cancer |
External Links
| Links for TMPO-AS1 | GenBank HGNC NONCODE |
| Links for bladder cancer | OMIM COSMIC |