Basic Information
| LncRNA/CircRNA Name | TNRC6C-AS1 |
| Synonyms | NA |
| Region | GRCh38_17:78107398-78111799 |
| Ensemble | ENSG00000204282 |
| Refseq | NR_040071 |
Classification Information
| Regulatory Mechanism | Biological Function | Clinical Application | |||
|---|---|---|---|---|---|
| TF | Immune | Survival | |||
| Enhancer | Apoptosis | apoptosis | Drug | ||
| Variant | Cell Growth | Circulating | |||
| MiRNA | EMT | Metastasis | |||
| Methylation | Coding Ability | Recurrence |
Cancer&Entry Information
| Cancer Name | thyroid cancer |
| ICD-0-3 | C73.9 |
| Methods | qPCR, Luciferase reporter assay, Western blot, Microarray |
| Sample | TC tissues,cell line(FRO,ARO, PDTC-1,SW579) |
| Expression Pattern | up-regulated |
| Function Description | TNRC6C-AS1 was up-regulated but STK4 was markedly down-regulated in the OE-TNRC6C group |
| Pubmed ID | 30938030 |
| Year | 2019 |
| Title | Suppression of long non-coding RNA TNRC6C-AS1 protects against thyroid carcinoma through DNA demethylation of STK4 via the Hippo signalling pathway. |
External Links
| Links for TNRC6C-AS1 | GenBank HGNC NONCODE |
| Links for thyroid cancer | OMIM COSMIC |