Basic Information
| LncRNA/CircRNA Name | TP53TG1 |
| Synonyms | TP53TG1, LINC00096, NCRNA00096, P53TG1, P53TG1-D, TP53AP1 |
| Region | GRCh38_7:87325225-87345515 |
| Ensemble | ENSG00000182165 |
| Refseq | NR_015381 |
Classification Information
| Regulatory Mechanism | Biological Function | Clinical Application | |||
|---|---|---|---|---|---|
| TF | Immune | Survival | |||
| Enhancer | Apoptosis | Drug | |||
| Variant | Cell Growth | Circulating | |||
| MiRNA | EMT | Metastasis | |||
| Methylation | Coding Ability | Recurrence |
Cancer&Entry Information
| Cancer Name | gastric cancer |
| ICD-0-3 | C16 |
| Methods | Microarray, MSP-PCR, Immunohistochemistry etc. |
| Sample | gastric cancer tissues, cell lines (MKN-45, MKN-7, TGBC11TKB, KATO-III, SNU-1 and GCIY) |
| Expression Pattern | differential expression |
| Function Description | We found TP53TG1 hypermethylation in 26% (45 of 173) of the gastric neoplasms studied. Presence of TP53TG1 hypermethylation was significantly associated with shorter progression-free survival. |
| Pubmed ID | 27821766 |
| Year | 2016 |
| Title | Epigenetic inactivation of the p53-induced long noncoding RNA TP53 target 1 in human cancer. |
External Links
| Links for TP53TG1 | GenBank HGNC NONCODE |
| Links for gastric cancer | OMIM COSMIC |