Basic Information
| LncRNA/CircRNA Name | TP73-AS1 |
| Synonyms | TP73 antisense RNA 1 |
| Region | NA |
| Ensemble | ENSG00000227372 |
| Refseq | NR_033708 |
Classification Information
| Regulatory Mechanism | Biological Function | Clinical Application | |||
|---|---|---|---|---|---|
| TF | Immune | Survival | |||
| Enhancer | Apoptosis | Drug | |||
| Variant | Cell Growth | Circulating | |||
| MiRNA | EMT | Metastasis | |||
| Methylation | Coding Ability | Recurrence |
Cancer&Entry Information
| Cancer Name | gastric cancer |
| ICD-0-3 | C16 |
| Methods | qPCR, Luciferase reporter assay etc. |
| Sample | GC and adjacent tissues,cell lines (AGS,SNU-1) |
| Expression Pattern | down-regulated |
| Function Description | Cell invasion and migration assays showed that miR-223-5p could promote the invasion and migration of gastric cancer cells, while TP73-AS1 could inhibit the invasion and migration of gastric cancer cells. In addition, miR-223-5p attenuated the effects of TP73-AS1 overexpression. Therefore, miR-223-5p may target TP73-AS1 to promote the invasion and migration of gastric cancer patients |
| Pubmed ID | 32248369 |
| Year | 2020 |
| Title | MicroRNA-223-5p Targets Long Non-Coding RNA TP73 Antisense RNA1 to Promote the Invasion of Gastric Cancer |
External Links
| Links for TP73-AS1 | GenBank HGNC NONCODE |
| Links for gastric cancer | OMIM COSMIC |