Basic Information
| LncRNA/CircRNA Name | TP73-AS1 |
| Synonyms | TP73-AS1, KIAA0495, PDAM |
| Region | NA |
| Ensemble | ENSG00000227372 |
| Refseq | NR_033708 |
Classification Information
| Regulatory Mechanism | Biological Function | Clinical Application | |||
|---|---|---|---|---|---|
| TF | Immune | Survival | |||
| Enhancer | Apoptosis | Drug | |||
| Variant | Cell Growth | Circulating | |||
| MiRNA | EMT | Metastasis | |||
| Methylation | Coding Ability | Recurrence |
Cancer&Entry Information
| Cancer Name | gastric cancer |
| ICD-0-3 | C16 |
| Methods | qPCR, Western blot, Luciferase reporter assay, other |
| Sample | GC tissues and cell lines (MGC-803, SGC-7901, BGC-823, MKN-28, AGS, GES-1) |
| Expression Pattern | up-regulated |
| Function Description | TP73-AS1 was upregulated in GC tissues and cell lines. Furthermore, TP73-AS1 exerted oncogenic role in GC through promoting cell growth and metastasis. In addition, TP73-AS1 was certified as a ceRNA by regulating miR-194-5p/SDAD1 axis. |
| Pubmed ID | 30279010 |
| Year | 2018 |
| Title | LncRNA TP73-AS1 Accelerates Tumor Progression in Gastric Cancer Through Regulating miR-194-5p/SDAD1 Axis |
External Links
| Links for TP73-AS1 | GenBank HGNC NONCODE |
| Links for gastric cancer | OMIM COSMIC |