Basic Information
| LncRNA/CircRNA Name | CASC15 |
| Synonyms | NA |
| Region | GRCh38_6:21664772-22368328 |
| Ensemble | ENSG00000272168 |
| Refseq | NR_015410 |
Classification Information
| Regulatory Mechanism | Biological Function | Clinical Application | |||
|---|---|---|---|---|---|
| TF | Immune | Survival | |||
| Enhancer | Apoptosis | Drug | |||
| Variant | Cell Growth | Circulating | |||
| MiRNA | EMT | Metastasis | |||
| Methylation | Coding Ability | Recurrence |
Cancer&Entry Information
| Cancer Name | tongue squamous cell carcinoma |
| ICD-0-3 | C02 |
| Methods | RT-qPCR |
| Sample | TSCC and adjacent non-cancer tissues,TSCC cell lines SCC25 and SCC090 |
| Expression Pattern | up-regulated |
| Function Description | CASC15 was upregulated, while miR-124 was downregulated in TSCC tissues than in non-cancer tissues of TSCC patients. CASC15 and miR-125 expression was not significantly different among patients with different clinical stages, and patients with high level of CASC15 and low level of miR-125 showed low overall survival rate.CASC15 overexpression resulted in the increased, while miR-124 overexpression resulted in the decreased migration and invasion rates of TSCC cells. |
| Pubmed ID | 31665008 |
| Year | 2019 |
| Title | LncRNA CACS15 Regulates Tongue Squamous Cell Carcinoma Cell Behaviors and Predicts Survival |
External Links
| Links for CASC15 | GenBank HGNC NONCODE |
| Links for tongue squamous cell carcinoma | OMIM COSMIC |