Basic Information
| LncRNA/CircRNA Name | TUG1 |
| Synonyms | TUG1, LINC00080, NCRNA00080, TI-227H |
| Region | GRCh38_22:30969245-30979395 |
| Ensemble | ENSG00000253352 |
| Refseq | NR_002323 |
Classification Information
| Regulatory Mechanism | Biological Function | Clinical Application | |||
|---|---|---|---|---|---|
| TF | Immune | Survival | |||
| Enhancer | Apoptosis | Drug | |||
| Variant | Cell Growth | Circulating | |||
| MiRNA | EMT | Metastasis | |||
| Methylation | Coding Ability | Recurrence |
Cancer&Entry Information
| Cancer Name | gastric cancer |
| ICD-0-3 | C16 |
| Methods | qPCR, RNAi etc. |
| Sample | cell lines (AGS1, MGC803, SGC7901, and MKN53), gastric adenocarcinomas tissues |
| Expression Pattern | up-regulated |
| Function Description | The expression pattern indicated that MALAT1 synchronize the expression level of KLF4 and miR-145 and MALAT1 had a strong impact than TUG1 in regulating KLF4 through sponging miR-145. |
| Pubmed ID | 29719612 |
| Year | 2018 |
| Title | Comprehensive analysis of aberrantly expressed lncRNAs and construction of ceRNA network in gastric cancer. |
External Links
| Links for TUG1 | GenBank HGNC NONCODE |
| Links for gastric cancer | OMIM COSMIC |