Basic Information
| LncRNA/CircRNA Name | CASC15 |
| Synonyms | CASC15, LINC00340, lnc-SOX4-1 |
| Region | GRCh38_6:21664772-22368328 |
| Ensemble | ENSG00000272168 |
| Refseq | NR_015410 |
Classification Information
| Regulatory Mechanism | Biological Function | Clinical Application | |||
|---|---|---|---|---|---|
| TF | Immune | Survival | |||
| Enhancer | Apoptosis | Drug | |||
| Variant | Cell Growth | Circulating | |||
| MiRNA | EMT | Metastasis | |||
| Methylation | Coding Ability | Recurrence |
Cancer&Entry Information
| Cancer Name | tongue squamous cell carcinoma |
| ICD-0-3 | C02 |
| Methods | qPCR, Western blot etc. |
| Sample | tongue squamous cell carcinoma tissues, cell lines (SCC1, SCC4,Cal27, and UM1) |
| Expression Pattern | up-regulated |
| Function Description | Here, we identified that CASC15 expression was upregulated in TSCC samples and cell lines. Elevated expression of CASC15 suppressed miR-33a-5p expression and promoted ZEB1 expression in SCC4 cell. |
| Pubmed ID | 29804249 |
| Year | 2018 |
| Title | Long non-coding RNA CASC15 promotes tongue squamous carcinoma progression through targeting miR-33a-5p |
External Links
| Links for CASC15 | GenBank HGNC NONCODE |
| Links for tongue squamous cell carcinoma | OMIM COSMIC |