Basic Information
| LncRNA/CircRNA Name | TUG1 |
| Synonyms | TUG1, LINC00080, NCRNA00080, TI-227H |
| Region | GRCh38_22:30969245-30979395 |
| Ensemble | ENSG00000253352 |
| Refseq | NR_002323 |
Classification Information
| Regulatory Mechanism | Biological Function | Clinical Application | |||
|---|---|---|---|---|---|
| TF | Immune | Survival | |||
| Enhancer | Apoptosis | Drug | |||
| Variant | Cell Growth | Circulating | |||
| MiRNA | EMT | Metastasis | |||
| Methylation | Coding Ability | Recurrence |
Cancer&Entry Information
| Cancer Name | osteosarcoma |
| ICD-0-3 | NA |
| Methods | qPCR, Luciferase Reporter Assays, RIP |
| Sample | Osteosarcoma tissues, cell lines (MG63 and U2-OS) |
| Expression Pattern | down-regulated |
| Function Description | TUG1 was overexpressed and miR-153 was downregulated in osteosarcoma tissues and cell lines. Moreover, TUG1 was confirmed to be a miR-153 sponge. |
| Pubmed ID | 28411362 |
| Year | 2017 |
| Title | Knockdown of Long Noncoding RNA TUG1 Inhibits the Proliferation and Cellular Invasion of Osteosarcoma Cells By Sponging MiR-153 |
External Links
| Links for TUG1 | GenBank HGNC NONCODE |
| Links for osteosarcoma | OMIM COSMIC |