Basic Information
LncRNA/CircRNA Name | TUG1 |
Synonyms | TUG1, LINC00080, NCRNA00080, TI-227H |
Region | GRCh38_22:30969245-30979395 |
Ensemble | ENSG00000253352 |
Refseq | NR_002323 |
Classification Information
Regulatory Mechanism | Biological Function | Clinical Application | |||
---|---|---|---|---|---|
TF | Immune | Survival | |||
Enhancer | Apoptosis | Drug | |||
Variant | Cell Growth | Circulating | |||
MiRNA | EMT | Metastasis | |||
Methylation | Coding Ability | Recurrence |
Cancer&Entry Information
Cancer Name | osteosarcoma |
ICD-0-3 | NA |
Methods | qPCR, Luciferase Reporter Assays, RIP |
Sample | Osteosarcoma tissues, cell lines (MG63 and U2-OS) |
Expression Pattern | down-regulated |
Function Description | TUG1 was overexpressed and miR-153 was downregulated in osteosarcoma tissues and cell lines. Moreover, TUG1 was confirmed to be a miR-153 sponge. |
Pubmed ID | 28411362 |
Year | 2017 |
Title | Knockdown of Long Noncoding RNA TUG1 Inhibits the Proliferation and Cellular Invasion of Osteosarcoma Cells By Sponging MiR-153 |
External Links
Links for TUG1 | GenBank HGNC NONCODE |
Links for osteosarcoma | OMIM COSMIC |