Basic Information
| LncRNA/CircRNA Name | CASC2 |
| Synonyms | NA |
| Region | GRCh38_10:118046279-118210153 |
| Ensemble | ENSG00000177640 |
| Refseq | NR_026939 |
Classification Information
| Regulatory Mechanism | Biological Function | Clinical Application | |||
|---|---|---|---|---|---|
| TF | Immune | Survival | |||
| Enhancer | Apoptosis | apoptosis | Drug | ||
| Variant | Cell Growth | Circulating | |||
| MiRNA | EMT | Metastasis | |||
| Methylation | Coding Ability | Recurrence |
Cancer&Entry Information
| Cancer Name | oral squamous cell carcinoma |
| ICD-0-3 | C06.9 |
| Methods | RT-qPCR, Western blot |
| Sample | OSCC tissues,cell lines |
| Expression Pattern | down-regulated |
| Function Description | CASC2/miR-21/PDCD4 axis might be a potential regulator of OSCC tumorigenesis, and shed new light on lncRNA-directed diagnostics and therapeutics in OSCC. |
| Pubmed ID | 32009793 |
| Year | 2019 |
| Title | Long non-coding RNA CASC2 serves as a ceRNA of microRNA-21 to promote PDCD4 expression in oral squamous cell carcinoma |
External Links
| Links for CASC2 | GenBank HGNC NONCODE |
| Links for oral squamous cell carcinoma | OMIM COSMIC |